Partial absence of pleuropericardial membranes in Tbx18- and Wt1-deficient mice.
The pleuropericardial membranes are fibro-serous walls that separate the pericardial and pleural cavities and anchor the heart inside the mediastinum.Partial or complete absence of pleuropericardial membranes is a rare human disease, the etiology of which is poorly understood.As an attempt click here to better understand these defects, we wished to